MYOCARDIAL STIMULATION BY PANCURONIUM BROMIDE
نویسندگان
چکیده
منابع مشابه
Myocardial stimulation by pancuronium bromide.
The effect of pancuronium bromide on the canine myocardium was studied by observing several indices of myocardial contractility during i.v. and intracoronary infusion of the drug in an anaesthetized, open-chested dog preparation. Pancuronium produced tachycardia when given for 2 min by i.v. and intracoronary infusion with the heart intact. Following denervation and pacing of the heart the intra...
متن کاملComparative potency of pipecuronium bromide and pancuronium bromide.
Cumulative dose-response curves were constructed to determine the comparative potency of pipecuronium and pancuronium. From these, the ED50 and ED95 values were calculated. These were 24.96 micrograms kg-1 and 44.96 micrograms kg-1, respectively, for pipecuronium and 30.42 micrograms kg-1 and 61.12 micrograms kg-1, respectively, for pancuronium.
متن کاملPancuronium bromide induced joint contractures in the newborn.
We report three infants paralysed with pancuronium bromide as an adjunct to mechanical ventilation, who developed multiple joint contractures. In two term infants, gentamicin and phenobarbitone given together with pancuronium may have potentiated its effect, and in one preterm infant contractures, which became more severe after paralysis, were present at birth.
متن کاملCombined i.v. bolus and infusion of pancuronium bromide.
An i.v. bolus and concomitant infusion of pancuronium is proposed for use in prolonged anaesthesia. Plasma concentrations of pancuronium were measured in 16 patients receiving this regime. The desired steady-state concentration of 0.2 fig ml" was achieved in most instances at approximately 45 min. Following the bolus, the neuromuscular twitch response decreased to low values or was abolished co...
متن کاملClinical Evaluation of Pipecuronium Bromide and its Comparison with Pancuronium Bromide
The study was carried out to compare the intubating conditions, cardiovascular responses, neuro-muscular blocking properties and reversal characteristics of pipecuronium bromide and pancuronium bromide. This is a prospective hospital based study. 100 patients belonging to ASA grade I or II physical status aged 18 to 70 years were divided into two groups of 50 patients each. Group 1 received pip...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1977
ISSN: 0007-0912
DOI: 10.1093/bja/49.5.401